Compound Q&A

How is 1-Chloro-3-methylisoquinoline (CAS: 7115-16-4) typically synthesized?

Answer

1-Chloro-3-methylisoquinoline
1-Chloro-3-methylisoquinoline (CAS: 7115-16-4) can be synthesized via the chlorination of 3-methylisoquinoline using thionyl chloride as the chlorinating agent. This method provides good selectivity and yield. Alternatively, it can be prepared from 1-methylisoquinoline via a chlorination reaction with a Lewis acid such as aluminum chloride.

About

CAS No 7115-16-4
English Name 1-Chloro-3-methylisoquinoline
Molecular Formula C10H8ClN
Molecular Weight 177.63 g/mol
SMILES CC1=CC2=CC=CC=C2C(=N1)Cl
InChIKey RWAHYDUCMPRQOP-UHFFFAOYSA-N
Last Updated: 2026-01-07 05:52

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