Compound Q&A

Are there alternatives to 6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3,4'-trioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane) (CAS: 219719-95-6) in synthesis?

Answer

6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3,4'-trioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane)
Alternatives include using isomers or analogs, such as 6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3-dioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane), which can serve as effective substitutes in many synthetic pathways. Common alternative reagents may include fluorine-containing reagents like trifluoromethanesulfonic acid for fluoroalkylation reactions.

About

English Name 6alpha,9alpha-Difluoro-11beta-hydroxy-16alpha-methyl-2',3,4'-trioxo-17alpha-spiro(androsta-1,4-diene-17,5'-(1,3)oxathiolane)
Molecular Formula C22H24F2O5S
Molecular Weight 438.49 g/mol
SMILES CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C15C(=O)SC(=O)O5)C)O)F)C)F
InChIKey IYYYTOVWCWEIIH-KVNRZBMZSA-N
Last Updated: 2026-01-05 18:36

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