Compound Q&A
How is 6-[(2-Chloro-5-fluoro-4-pyrimidinyl)amino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one (CAS: 575484-83-2) typically synthesized?
Answer
![6-[(2-Chloro-5-fluoro-4-pyrimidinyl)amino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one](https://static.chemtradehub.com/structs/575/575484-83-2-2963.webp "6-[(2-Chloro-5-fluoro-4-pyrimidinyl)amino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one")
6-[(2-Chloro-5-fluoro-4-pyrimidinyl)amino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one is synthesized through a multi-step process involving the coupling of 2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one with 2-chloro-5-fluoro-4-pyrimidinamine. This reaction is typically carried out in the presence of a base and a suitable solvent. The yield is around 75-80% and the process is highly selective.
About
CAS No
575484-83-2
English Name
6-[(2-Chloro-5-fluoro-4-pyrimidinyl)amino]-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one
Molecular Formula
C13H11ClFN5O2
Molecular Weight
323.72 g/mol
SMILES
O=C1NC2=NC(NC3=NC(Cl)=NC=C3F)=CC=C2OC1(C)C
InChIKey
IBQYILNHUAYCHB-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
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