Compound Q&A
How is 5-(3-Bromophenyl)-1,3,4-oxadiazol-2(3H)-one (CAS: 873090-18-7) typically synthesized?
Answer
5-(3-Bromophenyl)-1,3,4-oxadiazol-2(3H)-one can be synthesized by bromination of 3-phenylbenzaldehyde followed by reaction with sodium hydroxide and oxalyl chloride. The synthesis involves the use of a phase-transfer catalyst such as tetra-n-butylammonium hydroxide to enhance the reaction yield. The final product is obtained with good yield and selectivity.
About
CAS No
873090-18-7
English Name
5-(3-Bromophenyl)-1,3,4-oxadiazol-2(3H)-one
Molecular Formula
C8H5BrN2O2
Molecular Weight
241.04 g/mol
SMILES
C1=CC(=CC(=C1)Br)C2=NNC(=O)O2
InChIKey
ZVWSHDFGLFCEID-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
