Compound Q&A

How is Methyl 3-(4-methylphenoxy)benzoate (CAS: 78303-09-0) typically synthesized?

Answer

Methyl 3-(4-methylphenoxy)benzoate
Methyl 3-(4-methylphenoxy)benzoate can be synthesized via esterification of 3-(4-methylphenoxy)benzoic acid with methanol in the presence of a catalytic amount of sulfuric acid. The reaction typically provides a yield of around 85%. The process involves heating the mixture to 60-70°C for several hours, followed by neutralization with a base and subsequent purification through recrystallization.

About

CAS No 78303-09-0
English Name Methyl 3-(4-methylphenoxy)benzoate
Molecular Formula C15H14O3
Molecular Weight 242.274 g/mol
SMILES CC1=CC=C(C=C1)OC2=CC=CC(=C2)C(=O)OC
InChIKey DPSCCQUGLOXIEJ-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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