Compound Q&A
How is 2-Chloro-1H-indole (CAS: 7135-31-1) typically synthesized?
Answer
2-Chloro-1H-indole can be synthesized via various methods, including the Claisen condensation of indole with 2-chloroacetic acid followed by amination. Another route involves the reaction of indole with chloromethyl ketone using a Lewis acid catalyst. The yield and selectivity can vary, but these methods typically achieve good efficiency.
About
CAS No
7135-31-1
English Name
2-Chloro-1H-indole
Molecular Formula
C8H6ClN
Molecular Weight
151.6 g/mol
SMILES
C1=CC=C2C(=C1)C=C(N2)Cl
InChIKey
HBZHNVUMFPGVHW-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
