Compound Q&A

How is 2',3',5',6'-Tetramethyl-1,1':4',1''-terphenyl-4,4''-dicarbaldehyde (CAS: 850559-54-5) typically synthesized?

Answer

2',3',5',6'-Tetramethyl-1,1':4',1''-terphenyl-4,4''-dicarbaldehyde
2',3',5',6'-Tetramethyl-1,1':4',1''-terphenyl-4,4''-dicarbaldehyde is typically synthesized through a Hantzsch ester synthesis followed by a Wittig olefination. The reaction involves the use of methyl acetoacetate, an aryl methyl ketone, and a Grignard reagent. The process yields the compound with a high degree of selectivity and purity, often greater than 95%.

About

English Name 2',3',5',6'-Tetramethyl-1,1':4',1''-terphenyl-4,4''-dicarbaldehyde
Molecular Formula C24H22O2
Molecular Weight 342.44 g/mol
SMILES O=CC1=CC=C(C2=C(C)C(C)=C(C3=CC=C(C=O)C=C3)C(C)=C2C)C=C1
InChIKey SOGBYRYNMDXUPO-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14

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