Compound Q&A
How is 5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS: 652148-93-1) typically synthesized?
Answer
5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is typically synthesized through a boronation reaction of 5-chloropyridine with 4,4,5,5-tetramethyl-2-borono-1,3,2-dioxaborolane in the presence of a palladium catalyst and a base such as potassium carbonate. The reaction yields a pure product with high selectivity and good yield.
About
CAS No
652148-93-1
English Name
5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Molecular Formula
C11H15BClNO2
Molecular Weight
239.51 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=NC=C(C=C2)Cl
InChIKey
RWOCXFPQPISTSD-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
