Compound Q&A
How is 5-Bromo-1,2-dimethyl-3-(trifluoromethyl)benzene (CAS: 80245-29-0) typically synthesized?
Answer
5-Bromo-1,2-dimethyl-3-(trifluoromethyl)benzene is synthesized through a Friedel-Crafts alkylation of 1,2-dimethyl-3-(trifluoromethyl)benzene with N-bromosuccinimide (NBS) in the presence of a radical initiator like benzoyl peroxide. The reaction is typically performed at room temperature and provides good selectivity and yield.
About
CAS No
80245-29-0
English Name
5-Bromo-1,2-dimethyl-3-(trifluoromethyl)benzene
Molecular Formula
C9H8BrF3
Molecular Weight
253.06 g/mol
SMILES
Cc1cc(cc(c1C)C(F)(F)F)Br
InChIKey
AINASRYWSBKQSE-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
