Compound Q&A
How is 1-Methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine (CAS: 914610-39-2) typically synthesized?
Answer
![1-Methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine](https://static.chemtradehub.com/structs/914/914610-39-2-2ea2.webp "1-Methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine")
1-Methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine is typically synthesized via the coupling of 4-bromobenzene sulfonyl chloride with 1-methylpiperazine in the presence of a borate ester and a catalytic amount of a palladium complex, such as Pd(PPh3)4. The reaction is carried out under mild conditions, leading to high yields and good selectivity.
About
CAS No
914610-39-2
English Name
1-Methyl-4-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl]piperazine
Molecular Formula
C17H27BN2O4S
Molecular Weight
366.29 g/mol
SMILES
B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)S(=O)(=O)N3CCN(CC3)C
InChIKey
TZMSTBRAQGYDJI-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
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