Compound Q&A
How is 3-Bromo-5-fluoro-2-methylbenzoic acid (CAS: 1187318-52-0) typically synthesized?
Answer
3-Bromo-5-fluoro-2-methylbenzoic acid is commonly synthesized via bromination and fluorination of 2-methylbenzoic acid. The reaction typically involves the use of N-bromosuccinimide (NBS) or N-fluoroboric acid in the presence of a radical initiator. The yield is usually around 70-80%, and the product can be isolated by recrystallization from an appropriate solvent.
About
CAS No
1187318-52-0
English Name
3-Bromo-5-fluoro-2-methylbenzoic acid
Molecular Formula
C8H6BrFO2
Molecular Weight
233.04 g/mol
SMILES
Cc1c(cc(cc1Br)F)C(=O)O
InChIKey
AAKUFRPQXGQYHN-UHFFFAOYSA-N
Last Updated: 2026-01-04 19:14
