Compound Q&A

How is 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile (CAS: 799270-07-8) typically synthesized?

Answer

5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
5-Bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile is synthesized through the bromination of 1H-pyrrolo[2,3-b]pyridine-3-carbonitrile. The reaction is typically performed using N-bromosuccinimide (NBS) as the brominating agent in the presence of a suitable radical initiator like AIBN. The reaction yields a high percentage of the desired product with good selectivity.

About

English Name 5-bromo-1H-pyrrolo[2,3-b]pyridine-3-carbonitrile
Molecular Formula C8H4BrN3
Molecular Weight 222.04 g/mol
SMILES C1=C(C=NC2=C1C(=CN2)C#N)Br
InChIKey WDUMYOXRHLWOIR-UHFFFAOYSA-N
Last Updated: 2026-01-02 00:31

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