Compound Q&A
How is 2-[(1S)-1-Aminoethyl]-4-chlorophenol (CAS: 1228569-39-8) typically synthesized?
Answer
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2-[(1S)-1-Aminoethyl]-4-chlorophenol can be synthesized via a multistep process involving the reaction of 4-chlorophenol with ethylamine. The key steps include the substitution of the chlorine atom with aminoethyl group. Catalysts such as sodium ethoxide or potassium hydroxide are used to improve yield and selectivity. The overall process involves protecting the phenolic hydroxyl group, amide formation, and subsequent deprotection to yield the desired product.
About
CAS No
1228569-39-8
English Name
2-[(1S)-1-Aminoethyl]-4-chlorophenol
Molecular Formula
C8H10ClNO
Molecular Weight
171.63 g/mol
SMILES
CC(C1=C(C=CC(=C1)Cl)O)N
InChIKey
IHDFZQZUBQSKDM-YFKPBYRVSA-N
Last Updated: 2026-01-01 20:06
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