Compound Q&A
How is Pitavastatin Defuoro IMpurity CalciuM Salt (CAS: 1258947-30-6) typically synthesized?
Answer
Pitavastatin Defuoro IMpurity CalciuM Salt (CAS: 1258947-30-6) is typically synthesized through a multi-step process involving the modification of pitavastatin structure, followed by calcium salt formation. Key steps include the introduction of a defuorinated group using appropriate reagents, followed by calcium salt formation. The process often employs mild conditions and uses a variety of solvents. The yield is typically around 80-90%, and the reaction is performed under an inert atmosphere to prevent oxidation.
About
CAS No
1258947-30-6
English Name
Pitavastatin Defuoro IMpurity CalciuM Salt
Molecular Formula
C50H50CaN2O8
Molecular Weight
847.02 g/mol
SMILES
[Ca].O([H])[C@@]([H])(C([H])([H])[C@]([H])(C([H])([H])C(=O)O[H])O[H])/C(/[H])=C(\[H])/C1=C(C2C([H])=C([H])C([H])=C([H])C=2[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C1([H])C([H])([H])C1([H])[H].O([H])[C@@]([H])(C([H])([H])[C@]([H])(C([H])([H])C(=O)O[H])O[H])/C(/[H])=C(\[H])/C1=C(C2C([H])=C([H])C([H])=C([H])C=2[H])C2=C([H])C([H])=C([H])C([H])=C2N=C1C1([H])C([H])([H])C1([H])[H]
InChIKey
VAUZHDOGZAAZHF-OFRWZBIKSA-N
Last Updated: 2026-01-01 20:06
