Compound Q&A

How is Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Glu-Pro-Arg (CAS: 120944-72-1) typically synthesized?

Answer

Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Glu-Pro-Arg
Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Glu-Pro-Arg (CAS: 120944-72-1) can be synthesized via solid-phase peptide synthesis using Fmoc chemistry. Commonly, the reaction is carried out using a Boc-protected amino acid sequence, followed by deprotection and coupling steps. The overall yield is typically around 70-80%, with high selectivity towards the desired product.

About

English Name Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Glu-Pro-Arg
Molecular Formula C65H98N16O19
Molecular Weight 1407.6 g/mol
SMILES CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C2CCCN2C(=O)C(CC(=O)O)NC(=O)C3CCCN3C(=O)C(CC4=CC=C(C=C4)O)NC(=O)C5CCCN5C(=O)C(C(C)C)NC(=O)C6CCCN6C(=O)C(C)NC(=O)CN
InChIKey XEVUUFOXAJNOGZ-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:35

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