Compound Q&A
How is 6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine (CAS: 205171-05-7) typically synthesized?
Answer
6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine can be synthesized through the condensation of 6-chloropurine and D-ribofuranosyl chloride. The reaction typically requires a catalytic amount of a Lewis acid such as aluminum chloride. The yield is around 75%, and the product is isolated by recrystallization from ethanol.
About
CAS No
205171-05-7
English Name
6-Chloro-9-(2-C-methyl-beta-D-ribofuranosyl)-9H-purine
Molecular Formula
C11H13ClN4O4
Molecular Weight
300.702 g/mol
SMILES
CC1(C(C(OC1N2C=NC3=C2N=CN=C3Cl)CO)O)O
InChIKey
MOMRKSMRPOKFCN-YRKGHMEHSA-N
Last Updated: 2026-01-01 15:34
