Compound Q&A

How is Chloroacetamido-PEG4-NHS Ester (CAS: 1353011-95-6) typically synthesized?

Answer

Chloroacetamido-PEG4-NHS Ester
Chloroacetamido-PEG4-NHS Ester (CAS: 1353011-95-6) is synthesized by reacting PEG4-NHS Ester with chloroacetyl chloride in the presence of a suitable solvent and a base. The reaction yields a high purity product with good selectivity and a high yield. The key steps involve the formation of an amide bond via an acyl chlorination reaction.

About

English Name Chloroacetamido-PEG4-NHS Ester
Molecular Formula C17H27ClN2O9
Molecular Weight 438.86 g/mol
SMILES ClCC(=O)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChIKey BPWFCYSNJLMFRO-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34

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