Compound Q&A

How is 1,4-Bis[(4-methylphenyl)sulfonyl]piperazine (CAS: 17046-84-3) typically synthesized?

Answer

1,4-Bis[(4-methylphenyl)sulfonyl]piperazine
1,4-Bis[(4-methylphenyl)sulfonyl]piperazine (CAS: 17046-84-3) can be synthesized through a multi-step process involving sulfonylation of piperazine with 4-methylbenzenesulfonyl chloride. Commonly used catalysts include phosphorus oxychloride, and the process proceeds with high selectivity, yielding a product with good purity.

About

CAS No 17046-84-3
English Name 1,4-Bis[(4-methylphenyl)sulfonyl]piperazine
Molecular Formula C18H22N2O4S2
Molecular Weight 394.52 g/mol
SMILES CC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)S(=O)(=O)C3=CC=C(C=C3)C
InChIKey LMIXCJFVEQOWSQ-UHFFFAOYSA-N
Last Updated: 2026-01-01 15:34

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