Compound Q&A
How is (16alpha)-21-Chloro-16-methyl-3,20-dioxopregna-1,4,9(11)-trien-17-yl 2-furoate (CAS: 83880-65-3) typically synthesized?
Answer
(16alpha)-21-Chloro-16-methyl-3,20-dioxopregna-1,4,9(11)-trien-17-yl 2-furoate is synthesized through a multi-step process involving alkene oxidation, chlorination, and esterification reactions. The synthesis typically requires careful control of temperature and the use of specific catalysts to achieve high yield and selectivity. This compound is often prepared using a combination of reagents such as tert-butyl hydroperoxide, sodium hypochlorite, and 2-furoic acid.
About
CAS No
83880-65-3
English Name
(16alpha)-21-Chloro-16-methyl-3,20-dioxopregna-1,4,9(11)-trien-17-yl 2-furoate
Molecular Formula
C27H29ClO5
Molecular Weight
468.98 g/mol
SMILES
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4(C3=CC[C@@]2([C@]1(C(=O)CCl)OC(=O)c5ccco5)C)C
InChIKey
GSJLBVBYMSNTPZ-XACSLSAESA-N
Last Updated: 2026-01-01 15:34
