Compound Q&A
How is 4-Amino-1,3-dihydro-2H-benzimidazol-2-one (CAS: 75370-65-9) typically synthesized?
Answer
4-Amino-1,3-dihydro-2H-benzimidazol-2-one can be synthesized via the Friedel-Crafts alkylation of 2-benzimidazolone or by the condensation of 2-benzimidazolinone with ammonia. The reactions are typically catalyzed by Lewis acids such as aluminum trichloride. The yield is generally around 70-80%, with high selectivity for the desired product.
About
CAS No
75370-65-9
English Name
4-Amino-1,3-dihydro-2H-benzimidazol-2-one
Molecular Formula
C7H7N3O
Molecular Weight
149.15 g/mol
SMILES
C1=CC(=C2C(=C1)NC(=O)N2)N
InChIKey
BCUSTVNWMJXDSE-UHFFFAOYSA-N
Last Updated: 2026-01-01 10:50
