Compound Q&A
How is (S)-4-(4-((2-(3,5-diMethylphenyl)pyrrolidin-1-yl)Methyl)phenoxy)-3-fluorobenzamide (CAS: 1174130-61-0) typically synthesized?
Answer
(S)-4-(4-((2-(3,5-diMethylphenyl)pyrrolidin-1-yl)Methyl)phenoxy)-3-fluorobenzamide is synthesized through a multi-step process involving the coupling of a fluorobenzamide with a pyrrolidine derivative. The synthesis typically uses a palladium catalyst for the cross-coupling reaction, followed by amination to introduce the pyrrolidine moiety. The final product is obtained with high yield and good selectivity.
About
CAS No
1174130-61-0
English Name
(S)-4-(4-((2-(3,5-diMethylphenyl)pyrrolidin-1-yl)Methyl)phenoxy)-3-fluorobenzaMide
Molecular Formula
C26H27FN2O2
Molecular Weight
418.51 g/mol
SMILES
CC1=CC(=CC(=C1)C2CCCN2CC3=CC=C(C=C3)OC4=C(C=C(C=C4)C(=O)N)F)C
InChIKey
ZHPMYDSXGRRERG-DEOSSOPVSA-N
Last Updated: 2026-01-01 10:50
