Compound Q&A

How is Methyl 5-amino-6-iodo-2-pyridinecarboxylate (CAS: 872355-60-7) typically synthesized?

Answer

Methyl 5-amino-6-iodo-2-pyridinecarboxylate
Methyl 5-amino-6-iodo-2-pyridinecarboxylate (CAS: 872355-60-7) is typically synthesized via nucleophilic substitution of methyl 5-amino-2-pyridinecarboxylate with iodine in the presence of a suitable base such as potassium carbonate. The reaction is carried out in a suitable organic solvent like DMF, and it usually provides a high yield with good selectivity. Catalysts such as copper(II) acetate can also be used to enhance the reaction efficiency.

About

English Name Methyl 5-amino-6-iodo-2-pyridinecarboxylate
Molecular Formula C7H7IN2O2
Molecular Weight 278.04900000000004 g/mol
SMILES COC(=O)c1ccc(N)c(I)n1
InChIKey XYAWLFXZOHDXKP-UHFFFAOYSA-N
Last Updated: 2026-01-01 06:12

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