Compound Q&A
How is 2-Chloro-5,6-dimethylnicotinic acid (CAS: 120003-75-0) typically synthesized?
Answer
2-Chloro-5,6-dimethylnicotinic acid can be synthesized by the reaction of nicotinic acid with chloromethyl methyl ether in the presence of a base like sodium hydroxide. The synthesis typically involves a condensation reaction followed by a chlorination step. The yield is around 70-80%, and the reaction is carried out under mild conditions to ensure selectivity.
About
CAS No
120003-75-0
English Name
2-Chloro-5,6-dimethylnicotinic acid
Molecular Formula
C8H8ClNO2
Molecular Weight
185.61 g/mol
SMILES
Cc1cc(C(=O)O)c(Cl)nc1C
InChIKey
JGTHNXDWSRAIAT-UHFFFAOYSA-N
Last Updated: 2026-01-01 06:12
