Compound Q&A
How is Allopurinol EP Impurity B (CAS: 22407-20-1) typically synthesized?
Answer
Allopurinol EP Impurity B (CAS: 22407-20-1) is typically synthesized as a by-product during the production of allopurinol. The synthesis involves the condensation of 6-mercaptopurine with isouramil, followed by an acetylation step. The process requires careful control of temperature and pH to achieve high selectivity and yield. Catalysts such as acetic anhydride are commonly used for the acetylation step.
About
CAS No
22407-20-1
English Name
Allopurinol EP Impurity B
Molecular Formula
C5H6N4O2
Molecular Weight
154.13 g/mol
SMILES
O=C(C1=CNN=C1NC=O)N
InChIKey
MKVXRGIJTKYXPR-UHFFFAOYSA-N
Last Updated: 2025-12-31 16:27
