Compound Q&A

How is 3-(Chloromethyl)-1,2-oxazole (CAS: 57684-71-6) typically synthesized?

Answer

3-(Chloromethyl)-1,2-oxazole
3-(Chloromethyl)-1,2-oxazole can be synthesized via the Wittig reaction of 1,2-oxazole and methyl chloroformate. This method provides good yield and selectivity. Another approach involves the chloromethylation of 1,2-oxazole using thionyl chloride in the presence of a base.

About

CAS No 57684-71-6
English Name 3-(Chloromethyl)-1,2-oxazole
Molecular Formula C4H4ClNO
Molecular Weight 117.53 g/mol
SMILES C1=CON=C1CCl
InChIKey MKFCBJOVMMLPRT-UHFFFAOYSA-N
Last Updated: 2025-12-31 16:27

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