Compound Q&A

How is (2S,3R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-4-methylpentanoic acid (CAS: 929198-84-5) typically synthesized?

Answer

(2S,3R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-4-methylpentanoic acid
(2S,3R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-4-methylpentanoic acid is typically synthesized through the protection of an amino group using tert-butoxycarbonyl chemistry. This involves the reaction of 2-amino-3-hydroxy-4-methylpentanoic acid with tert-butyloxycarbonyl chloride in the presence of a base such as triethylamine. The reaction requires mild conditions and yields a high purity product.

About

English Name (2S,3R)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-4-methylpentanoic acid
Molecular Formula C11H21NO5
Molecular Weight 247.29 g/mol
SMILES CC(C)C(C(C(=O)O)NC(=O)OC(C)(C)C)O
InChIKey ISRKGGQOVLQWDW-JGVFFNPUSA-N
Last Updated: 2025-12-31 16:27

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