Compound Q&A

How is N~2~-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alpha-asparagine (CAS: 74244-17-0) typically synthesized?

Answer

N~2~-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alpha-asparagine
N~2~-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alpha-asparagine (CAS: 74244-17-0) is synthesized through the condensation of 2-methyl-2-propanol and aspartic acid, followed by an esterification step. This process involves the use of a catalyst such as DCC (dicyclohexylcarbodiimide) and is typically performed in anhydrous conditions to improve yield and selectivity. The reaction is carried out at room temperature and can yield up to 90% purity.

About

CAS No 74244-17-0
English Name N~2~-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alpha-asparagine
Molecular Formula C9H16N2O5
Molecular Weight 232.24 g/mol
SMILES CC(C)(C)OC(=O)NC(CC(=O)O)C(=O)N
InChIKey VKCARTLEXJLJBZ-YFKPBYRVSA-N
Last Updated: 2025-12-31 06:49

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