Compound Q&A

How is (3S)-3-(2-Thienylsulfanyl)butanoic acid (CAS: 133359-80-5) typically synthesized?

Answer

(3S)-3-(2-Thienylsulfanyl)butanoic acid
(3S)-3-(2-Thienylsulfanyl)butanoic acid can be synthesized via the reaction of 3-bromobutanoic acid with 2-thiols in the presence of a base such as potassium carbonate. The reaction is typically carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is generally moderate, and the product can be purified by recrystallization from ethanol.

About

English Name (3S)-3-(2-Thienylsulfanyl)butanoic acid
Molecular Formula C8H10O2S2
Molecular Weight 202.3 g/mol
SMILES CC(CC(=O)O)SC1=CC=CS1
InChIKey SIFFRIHCTBGQTC-LURJTMIESA-N
Last Updated: 2025-12-31 06:49

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