Compound Q&A
How is N,N-DimethylphosphoramidochloridicAcid[(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methylEster (CAS: 956139-21-2) typically synthesized?
Answer
![N,N-DimethylphosphoramidochloridicAcid[(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methylEster](https://static.chemtradehub.com/structs/956/956139-21-2-2852.webp "N,N-DimethylphosphoramidochloridicAcid[(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methylEster")
N,N-DimethylphosphoramidochloridicAcid[(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methylEster is synthesized via a multi-step process involving condensation, amidation, and esterification reactions. Common catalysts used include sodium hydride and TBTU. The reaction typically achieves a yield of 70-80% with excellent selectivity.
About
CAS No
956139-21-2
English Name
N,N-DimethylphosphoramidochloridicAcid[(2S,6R)-6-[4-(Benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-(triphenylmethyl)-2-morpholinyl]methylEster
Molecular Formula
C37H37ClN5O5P
Molecular Weight
698.16 g/mol
SMILES
CN(C)P(=O)(OCC1CN(CC(O1)N2C=CC(=NC2=O)NC(=O)C3=CC=CC=C3)C(C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)Cl
InChIKey
RCQVHNTXMQCQLT-AUIRFOQBSA-N
Last Updated: 2025-12-31 06:49
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