How is 5-(Trifluoromethyl)-1,3,4-thiadiazol-2(3H)-one (CAS: 84352-75-0) typically synthesized?

5-(Trifluoromethyl)-1,3,4-thiadiazol-2(3H)-one can be synthesized through the reaction of trifluoromethyl isocyanate with thiourea. The reaction involves the formation of an intermediate cyanuric fluoride derivative, which then undergoes nucleophilic substitution to form the final product. This process is carried out under basic conditions and typically yields 80-90% of the target compound.