Compound Q&A

How is (2S)-3-Bromo-2-methyl-1-propanol (CAS: 98244-48-5) typically synthesized?

Answer

(2S)-3-Bromo-2-methyl-1-propanol
(2S)-3-Bromo-2-methyl-1-propanol (CAS: 98244-48-5) is typically synthesized via bromination of 2-methyl-1-propanol using a phase transfer catalyst in an organic solvent. The reaction requires a controlled environment to maintain selectivity and yield. Commonly, this involves the use of a strong base like sodium hydride in a polar aprotic solvent such as N,N-dimethylformamide (DMF) or dimethyl sulfoxide (DMSO).

About

CAS No 98244-48-5
English Name (2S)-3-Bromo-2-methyl-1-propanol
Molecular Formula C4H9BrO
Molecular Weight 153.02 g/mol
SMILES CC(CO)CBr
InChIKey KIBOHRIGZMLNNS-SCSAIBSYSA-N
Last Updated: 2025-12-31 06:49

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