Compound Q&A

Are there alternatives to Di-tert-butyl(4-(trifluoromethyl)phenyl)phosphine (CAS: 1228182-34-0) in synthesis?

Answer

Di-tert-butyl(4-(trifluoromethyl)phenyl)phosphine
In the synthesis of certain organophosphorus compounds, Di-tert-butyl(4-(trifluoromethyl)phenyl)phosphine (CAS: 1228182-34-0) can be replaced by other phosphine compounds such as triphenylphosphine, tributylphosphine, or other substituted phosphines. These alternatives can offer similar reactivity but with different solubility and toxicity profiles. The selection of an alternative reagent depends on the specific reaction and desired product characteristics.

About

English Name Di-tert-butyl(4-(trifluoromethyl)phenyl)phosphine
Molecular Formula C15H22F3P
Molecular Weight 290.31 g/mol
SMILES CC(C)(C)P(C1=CC=C(C=C1)C(F)(F)F)C(C)(C)C
InChIKey ILWCCADVRXVLTN-UHFFFAOYSA-N
Last Updated: 2025-12-29 16:50

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