Compound Q&A

How is 4-(1,1,1,2,3,3,3-Heptafluoro-2-propanyl)-2-(trifluoromethyl)aniline (CAS: 1207314-85-9) typically synthesized?

Answer

4-(1,1,1,2,3,3,3-Heptafluoro-2-propanyl)-2-(trifluoromethyl)aniline
4-(1,1,1,2,3,3,3-Heptafluoro-2-propanyl)-2-(trifluoromethyl)aniline (CAS: 1207314-85-9) can be synthesized via a multi-step process involving the reaction of 2,2,2-trifluoroethanol with 1,1,1,2,3,3,3-heptafluoro-2-propanol, followed by an alkylation step using 2,2,2-trifluoroethyl triflate. This synthesis typically requires the use of a phase transfer catalyst and generates a high yield of the target compound. The reaction is selective and efficient, with minimal by-products.

About

English Name 4-(1,1,1,2,3,3,3-Heptafluoro-2-propanyl)-2-(trifluoromethyl)aniline
Molecular Formula C10H5F10N
Molecular Weight 329.14 g/mol
SMILES c1cc(c(cc1C(C(F)(F)F)(C(F)(F)F)F)C(F)(F)F)N
InChIKey JNVWIZVZNZAVRK-UHFFFAOYSA-N
Last Updated: 2025-12-29 01:16

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