Compound Q&A

How is 3-[(2-chlorophenyl)amino]-propanenitrile (CAS: 94-89-3) typically synthesized?

Answer

Propanenitrile, 3-[(2-chlorophenyl)amino]-
3-[(2-Chlorophenyl)amino]-propanenitrile is typically synthesized by the amination of 3-chloropropanenitrile with 2-chloroaniline. The reaction is catalyzed by a strong base such as potassium hydroxide. The process involves heating the mixture to promote the nucleophilic substitution reaction, leading to high selectivity and yield. The product is then purified by techniques such as recrystallization or distillation.

About

CAS No 94-89-3
English Name Propanenitrile, 3-[(2-chlorophenyl)amino]-
Molecular Formula C9H9ClN2
Molecular Weight 17.03 g/mol
SMILES C1=CC=C(C(=C1)NCCC#N)Cl
InChIKey WZAUNZSICROOPY-UHFFFAOYSA-N
Last Updated: 2025-12-29 01:16

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