Compound Q&A
How is 1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid (CAS: 268545-13-7) typically synthesized?
Answer
![1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid](https://static.chemtradehub.com/structs/268/268545-13-7-319f.webp "1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid")
The compound can be synthesized via a multi-step process that involves the condensation of an aryl aldehyde with a pyrrolo[3,4-b]pyridine derivative, followed by the introduction of cyclopropyl and methoxy groups. The key steps include protecting group strategies, selective functionalization, and the use of catalysts for enhanced yield and regioselectivity. Detailed reaction conditions can be found in the literature.
About
CAS No
268545-13-7
English Name
1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
Molecular Formula
C21H24FN3O4
Molecular Weight
401.44 g/mol
SMILES
COc1c(N2C[C@H]3CCCN[C@H]3C2)c(F)cc4c(=O)c(cn(C5CC5)c14)C(=O)O
InChIKey
FABPRXSRWADJSP-BZNIZROVSA-N
Last Updated: 2025-12-29 01:16
![1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid — ShenZhenZhenJiangShengWuJiShu Co Ltd](https://static.chemtradehub.com/suppliers/67cec9142b2de6e8e95a51e7/67cec9142b2de6e8e95a51e7-logo.webp){kind=logo}