Compound Q&A

How is 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-benzoxazole (CAS: 837392-66-2) typically synthesized?

Answer

5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-benzoxazole
5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-benzoxazole (CAS: 837392-66-2) is typically synthesized via a multistep process involving the protection of the benzoxazole ring followed by introduction of the tetramethyl-1,3,2-dioxaborolane moiety. Common methods include the use of boronic acids and palladium catalysts, with good yield and selectivity under mild conditions. The exact conditions may vary based on the starting materials and desired purity.

About

English Name 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-benzoxazole
Molecular Formula C13H16BNO3
Molecular Weight 245.09 g/mol
SMILES B1(OC(C(O1)(C)C)(C)C)C2=CC3=C(C=C2)ON=C3
InChIKey ODSQMJSTZMKVEO-UHFFFAOYSA-N
Last Updated: 2025-12-29 01:16

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