Compound Q&A

How is 2-Bromo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazole-4-carbonitrile (CAS: 854044-51-2) typically synthesized?

Answer

2-Bromo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazole-4-carbonitrile
2-Bromo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazole-4-carbonitrile (CAS: 854044-51-2) can be synthesized through a multistep process involving the reaction of imidazole with bromoethoxy derivatives in the presence of trimethylsilyl chloride. The synthesis typically requires the use of a catalyst and involves selective bromination followed by silyl ether formation, yielding the final product with high yield.

About

English Name 2-Bromo-1-{[2-(trimethylsilyl)ethoxy]methyl}-1H-imidazole-4-carbonitrile
Molecular Formula C10H16BrN3OSi
Molecular Weight 17.03 g/mol
SMILES N#CC1=CN(COCC[Si](C)(C)C)C(Br)=N1
InChIKey XDLFZSWZSHTGJY-UHFFFAOYSA-N
Last Updated: 2025-12-29 01:16

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