Compound Q&A
How is 3-(2-Chlorophenoxy)propanoic acid (CAS: 7170-45-8) typically synthesized?
Answer
3-(2-Chlorophenoxy)propanoic acid is typically synthesized via the Friedel-Crafts acylation of 2-chlorophenol with propanoyl chloride. The reaction is catalyzed by an aluminum chloride (AlCl₃) and proceeds under reflux conditions. The yield is generally high, around 80-90%, and the product is purified by recrystallization from water or ethanol.
About
CAS No
7170-45-8
English Name
3-(2-Chlorophenoxy)propanoic acid
Molecular Formula
C9H9ClO3
Molecular Weight
200.621 g/mol
SMILES
C1=CC=C(C(=C1)OCCC(=O)O)Cl
InChIKey
UZFYWLRSVDZCSF-UHFFFAOYSA-N
Last Updated: 2025-12-29 01:16
