Compound Q&A

How is 1-(1,3-Oxazol-4-yl)ethanone (CAS: 859046-10-9) typically synthesized?

Answer

1-(1,3-Oxazol-4-yl)ethanone
1-(1,3-Oxazol-4-yl)ethanone can be synthesized via the condensation of 4-chloro-1-ethoxymethylene-1,3-oxazole with sodium ethoxide in ethanol or via the reaction of 4-chlorothiazole with acetaldehyde using a suitable base. The reaction yields a moderately pure product with good selectivity and high yield.

About

English Name 1-(1,3-Oxazol-4-yl)ethanone
Molecular Formula C5H5NO2
Molecular Weight 111.1 g/mol
SMILES CC(=O)c1cocn1
InChIKey NGZJBIGWTNAOPZ-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55

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