Compound Q&A
How is 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide (CAS: 720690-73-3) typically synthesized?
Answer
![6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide](https://static.chemtradehub.com/structs/720/720690-73-3-4448.webp "6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide")
6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide is synthesized through multistep processes, typically involving the synthesis of the 2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl group, followed by coupling with 6-methylnicotinoyl chloride. Common catalysts and reagents include triethylamine and pyridine. The final step involves purification by recrystallization from ethanol or a suitable solvent mixture.
About
CAS No
720690-73-3
English Name
6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methylnicotinamide
Molecular Formula
C21H25N3O2
Molecular Weight
351.45 g/mol
SMILES
CNC(=O)C1=CN=C(C=C1)OC2=CC3=C(CCN(CC3)C4CCC4)C=C2
InChIKey
WROHEWWOCPRMIA-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
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