Compound Q&A
How is N,N'-(2-Chloro-5-methyl-1,4-phenylene)bis(3-oxobutanamide) (CAS: 41131-65-1) typically synthesized?
Answer
N,N'-(2-Chloro-5-methyl-1,4-phenylene)bis(3-oxobutanamide) can be synthesized via a multistep process involving chlorination of a phenol, followed by reaction with an amine and subsequent acylation. The reaction typically uses a strong base like sodium hydride and a coupling reagent such as EDC/HOBt. The yield is moderate, and the product is isolated by recrystallization. The exact conditions may vary based on desired purity and scale of synthesis.
About
CAS No
41131-65-1
English Name
N,N'-(2-Chloro-5-methyl-1,4-phenylene)bis(3-oxobutanamide)
Molecular Formula
C15H17ClN2O4
Molecular Weight
324.76 g/mol
SMILES
CC1=CC(=C(C=C1NC(=O)CC(=O)C)Cl)NC(=O)CC(=O)C
InChIKey
BXICAEQXJKTNSD-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55
