Compound Q&A

How is 1-(4-Aminophenoxy)-3-ethoxy-2-propanol (CAS: 94056-98-1) typically synthesized?

Answer

1-(4-Aminophenoxy)-3-ethoxy-2-propanol
1-(4-Aminophenoxy)-3-ethoxy-2-propanol can be synthesized via a multi-step process involving the protection of a primary alcohol, followed by nucleophilic substitution with a 4-aminophenol derivative. The reaction is typically catalyzed by a Lewis acid such as zinc chloride, and the yield is around 70-80% with good selectivity. The product is then purified by distillation or recrystallization.

About

CAS No 94056-98-1
English Name 1-(4-Aminophenoxy)-3-ethoxy-2-propanol
Molecular Formula C11H17NO3
Molecular Weight 211.26 g/mol
SMILES CCOCC(COC1=CC=C(C=C1)N)O
InChIKey XGLCTRQIEGPEPR-UHFFFAOYSA-N
Last Updated: 2025-12-28 19:55

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