Compound Q&A

How is 2-Aminomethyl-1-benzyl-piperidine (CAS: 170701-98-1) typically synthesized?

Answer

2-Aminomethyl-1-benzyl-piperidine
2-Aminomethyl-1-benzyl-piperidine can be synthesized via a multi-step process, including the protection of the primary amine, alkylation of the piperidine ring, and subsequent deprotection. Common synthetic routes involve the use of benzyl chloride as an alkylating agent, with catalysis by Lewis acids such as boron trifluoride. The yield is typically around 70-80%, and the selectivity is high, ensuring a pure product.

About

English Name 2-Aminomethyl-1-benzyl-piperidine
Molecular Formula C13H20N2
Molecular Weight 204.31700000000004 g/mol
SMILES C1CCN(C(C1)CN)CC2=CC=CC=C2
InChIKey DKWRQRNCULDABS-UHFFFAOYSA-N
Last Updated: 2025-12-28 14:56

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