Compound Q&A

How is 2-(2,3-Dihydro-1-benzofuran-5-yl)ethanol (CAS: 87776-76-9) typically synthesized?

Answer

2-(2,3-Dihydro-1-benzofuran-5-yl)ethanol
2-(2,3-Dihydro-1-benzofuran-5-yl)ethanol (CAS: 87776-76-9) is typically synthesized via a multistep process involving Friedel-Crafts alkylation followed by reduction. The reaction involves benzofuran and ethyl bromide in the presence of aluminum chloride to form the alkylated product, which is then reduced using sodium borohydride to obtain the alcohol. This method provides good yield and selectivity.

About

CAS No 87776-76-9
English Name 2-(2,3-Dihydro-1-benzofuran-5-yl)ethanol
Molecular Formula C10H12O2
Molecular Weight 164.2 g/mol
SMILES C1COC2=C1C=C(C=C2)CCO
InChIKey IPSIYKHOHYJGMO-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59

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