Compound Q&A
How is 4-(Chloromethyl)-2-phenyl-1,3-thiazole (CAS: 4771-31-7) typically synthesized?
Answer
4-(Chloromethyl)-2-phenyl-1,3-thiazole is typically synthesized via the reaction of chloromethylbenzene with thiazole in the presence of an acid catalyst such as p-toluenesulfonic acid. The process involves the nucleophilic substitution of the chlorine atom by the thiazole ring, yielding a high yield of the desired product with good selectivity.
About
CAS No
4771-31-7
English Name
4-(Chloromethyl)-2-phenyl-1,3-thiazole
Molecular Formula
C10H8ClNS
Molecular Weight
209.7 g/mol
SMILES
C1=CC=C(C=C1)C2=NC(=CS2)CCl
InChIKey
SVEGSFSFMLCNFF-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59
