Compound Q&A

How is 6-[4-(3-Chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione (CAS: 863588-32-3) typically synthesized?

Answer

6-[4-(3-Chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione
6-[4-(3-Chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione is synthesized through multistep procedures involving coupling reactions and piperazine derivatization. Common methods include using piperazine and chlorophenyl derivatives with appropriate protecting groups. The reaction typically requires a catalyst and is carried out in organic solvents at room temperature or under mild conditions to achieve high yields.

About

English Name 6-[4-(3-Chlorophenyl)-1-piperazinyl]-3-cyclohexyl-2,4(1H,3H)-pyrimidinedione
Molecular Formula C20H25ClN4O2
Molecular Weight 388.9 g/mol
SMILES c1cc(cc(c1)Cl)N2CCN(CC2)c3cc(=O)n(c(=O)[nH]3)C4CCCCC4
InChIKey CHMQQIFPOIZPIJ-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59

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