Compound Q&A
How is 5-(3-Methylphenyl)-1,3,4-thiadiazol-2-amine (CAS: 76074-47-0) typically synthesized?
Answer
5-(3-Methylphenyl)-1,3,4-thiadiazol-2-amine is usually synthesized via a reaction between 3-methylphenyl isocyanate and sodium thiocyanate, conducted in a suitable solvent such as dimethylformamide (DMF). The reaction is catalyzed by a small amount of a strong base like sodium hydroxide, and yields up to 95% of the target compound with good selectivity.
About
CAS No
76074-47-0
English Name
5-(3-Methylphenyl)-1,3,4-thiadiazol-2-amine
Molecular Formula
C9H9N3S
Molecular Weight
191.26 g/mol
SMILES
CC1=CC(=CC=C1)C2=NN=C(S2)N
InChIKey
LPOIZXBPFTXVAO-UHFFFAOYSA-N
Last Updated: 2025-12-28 06:21
