Compound Q&A
How is 3-Amino-4-chloro-N-(2-furylmethyl)benzamide (CAS: 852839-94-2) typically synthesized?
Answer
3-Amino-4-chloro-N-(2-furylmethyl)benzamide is commonly synthesized via the condensation of 4-chloro-3-nitrobenzoic acid with 2-furylmethylamine, followed by reduction of the nitro group to an amino group. The reaction typically involves the use of a reducing agent like sodium borohydride and a catalyst such as sodium hydroxide. The yield is around 75-80% with good selectivity for the desired product.
About
CAS No
852839-94-2
English Name
3-Amino-4-chloro-N-(2-furylmethyl)benzamide
Molecular Formula
C12H11ClN2O2
Molecular Weight
250.685 g/mol
SMILES
c1cc(oc1)CNC(=O)c2ccc(c(c2)N)Cl
InChIKey
RPJRPRMXOSCORN-UHFFFAOYSA-N
Last Updated: 2025-12-28 06:21
