Compound Q&A
How is 4-Phenyl-1,3-thiazol-2(3H)-one (CAS: 3884-31-9) typically synthesized?
Answer
4-Phenyl-1,3-thiazol-2(3H)-one can be synthesized via the condensation of 2-thiohydrazine hydrochloride with phenyl isocyanate. This reaction is typically carried out in the presence of a catalyst such as triethylamine, and the yield is generally good, around 85-90%. The product is purified by recrystallization from a suitable solvent.
About
CAS No
3884-31-9
English Name
4-Phenyl-1,3-thiazol-2(3H)-one
Molecular Formula
C9H7NOS
Molecular Weight
177.23 g/mol
SMILES
C1=CC=C(C=C1)C2=CSC(=O)N2
InChIKey
UXIWLHNMLDJWMF-UHFFFAOYSA-N
Last Updated: 2025-12-28 06:21
