Compound Q&A

Are there alternatives to Tadalafil (CAS: 171596-27-3) in synthesis?

Answer

Tadalafil, (6R,12aS)-
In synthesis, alternatives to Tadalafil include using related PDE5 inhibitors such as sildenafil, vardenafil, or avanafil. These alternatives can be used as starting materials or as intermediates in the synthesis of Tadalafil. Isomers and analogs, such as the 6R,12aS-isomer, are also relevant in the synthesis of Tadalafil, providing flexibility in the manufacturing process.

About

English Name Tadalafil, (6R,12aS)-
Molecular Formula C22H19N3O4
Molecular Weight 389.4110000000002 g/mol
SMILES CN1CC(=O)N2C(C1=O)CC3=C(C2C4=CC5=C(C=C4)OCO5)NC6=CC=CC=C36
InChIKey WOXKDUGGOYFFRN-HRAATJIYSA-N
Last Updated: 2025-12-26 07:10

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